Microbiome Analysis Laboratory



Javier Tamames de la Huerta

Group Leader



Carlos Pedrós-Alió

Group Leader







Research summary

Microbial communities (microbiomes) are key players in many scenarios, from how the biosphere works to industrial and biotechnological processes, as well as human health and wellness. We study microbiomes of diverse environments trying to learn the rules that govern the assemblage of these microbial communities. This knowledge will help to understand how they function, and to predict the effects of disturbances. Eventually, this will lead to rational design and manipulation of microbiomes.



Tamames J, Puente-Sánchez F. A Highly Portable, Fully Automatic Metagenomic Analysis Pipeline . Front Microbiol 2019; 9:3349

García-García N, Tamames J, Linz AM, Pedrós-Alió C, Puente-Sánchez F. Microdiversity ensures the maintenance of functional microbial communities under changing environmental conditions The ISME J 2019; 13: 2969-2983

Pedrós-Alió, C, Acinas, SG, Logares, R, and Massana, R. In J.M. Gasol and D. Kirchman (eds.) Microbial Ecology of the Oceans, 3rd edition, 2018 ISBN 978-1-119-10718-7

Alcamán-Arias ME, Pedrós-Alió C, Tamames J, Fernández C, Pérez-Pantoja D, Vásquez M and Díez B.Diurnal Changes in Active Carbon and Nitrogen Pathways Along the Temperature Gradient in Porcelana Hot Spring Microbial Mat Frontiers in Microbiology 2018; 9:2353.

González JM, Hernández L, Manzano I, Pedrós-Alió C.Quantifying the relative importance of phylogeny and environmental preferences as drivers of gene content in prokaryotic microorganisms. The ISME J 2019; 13: 1183-1197



We focus mostly on marine microbial communities, but we are actively working in many other microbiomes from different environments. We study extreme environments because their microbiotas show fascinating adaptations to the harsh conditions. We work with human-associated microbiomes, such as the gut and the vagina, because of their potential to improve our health. We are also interested in other habitats, such as wastewaters and soils.

We use mostly bioinformatics tools to study the composition and functionality of microbiomes. Metagenomics is the basis of our work, since it provides the basic material: DNA sequences from environmental samples. The analysis of these sequences informs about the presence of diverse organisms and the content of their genomes, and the latter can be linked to functionality. We also carry out experimental work addressing interactions between members of microbiomes.





Natalia García GarcíaPredoctoral scientist
Javier Tamames de la Huerta Principal investigator
Carlos Pedrós-Alió Principal investigator
Fernando Puente Postdoctoral scientist
Beatriz Cámara Gallego Postdoctoral scientist
Diego Esteban Jiménez Lalana Predoctoral scientist
Natalia García García Predoctoral scientist

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