The activity of the members of this Department is centred around different aspects of Structural Biology, covering from experimental to in silico approaches. Several groups of the Department are involved in services at the Centre, such as Proteomics, Electron Microscopy and X-ray Crystallography.
One of the main strengths of the Department is the presence of several groups involved in different aspects of advanced electron microscopy and image processing. Some of them share their interest for the analysis of virus morphogenesis, from the cellular domain to the molecular details of virus assembly and structure.
The Department also hosts the Coordinating node for the Spanish Proteomic Network, running several projects based on advanced methods in mass spectrometry, with emphasis in high throughput analyses of post-translational modifications.
Head of Department: José María Valpuesta
OUR RESEARCH GROUPS:
Cell-cell and virus-cell interactions. José María Casasnovas
Structure of macromolecular assemblies. José L. Carrascosa
Viral molecular machines. José R. Castón
Electron tomography and image processing of cell structures. José J. Fernández
Molecular Biophysics of DNA repair Nanomachines. Fernando Moreno-Herrero
Conformational – functional behaviour of proteins. Víctor Muñoz
Cell Structure Laboratory. Cristina Risco
Structural and physical determinants of viral assembly. Carmen San Martín
Structure and function of molecular chaperones. José María Valpuesta
Structural biology of viral fibres. Mark van Raaij