Nueva convocatoria para solicitar becas JAE de Introducción a la Investigación en centros del CSIC. Las 250 becas ofertadas becas están orientadas a estudiantes universitarios, especialmente aquellos en el último curso de grado universitario y tendrán una duración de 5 meses consecutivos, iniciándose en septiembre u octubre de 2020.
El plazo de presentación de solicitudes se ha vuelto a abrir y termina el 10 de junio (incluido)
El Centro Nacional de Biotecnología recibirá 11 estudiantes en el curso 2020-2021
16 de JULIO 2020: RESOLUCION DEFINITIVA publicada en la página del CSIC
Un equipo del CNB-CSIC ha demostrado ‘in vitro’ que el fa´rmaco plitidepsina bloquea la multiplicación del coronavirus humano HCoV-229E
Los investigadores probarán ahora la eficacia del fármaco contra un coronavirus SARS, similar al nuevo virus que causa la enfermedad Covid-19
Investigadores del Consejo Superior de Investigaciones Científicas (CSIC) han demostrado in vitro que el fármaco Aplidin (plitidepsina), descubierto por la farmacéutica española PharmaMar, y usado para tratar el mieloma, logra frenar la multiplicación del coronavirus HCoV-229E, que pertenece a la familia del nuevo coronavirus que ha provocado una pandemia. Ahora, los investigadores van a estudiar si este fármaco es efectivo también contra el coronavirus SARS, muy similar al SARS- CoV-2 que causa la enfermedad Covid-19. “Es un resultado prometedor”, apunta el virólogo Luis Enjuanes, que dirige junto a Isabel Sola el laboratorio de coronavirus del Centro Nacional de Biotecnología (CNB-CSIC), en Madrid.
Madrid 5 de marzo 2020, CNB-CSIC. Las oxilipinas son una familia de hormonas vegetales presentes en todas las plantas terrestres y algunas algas, con funciones en defensa vegetal.
La revista Current Biology publica hoy los resultados de un estudio evolutivo de genómica comparativa que identifica una función ancestral de las oxilipinas común a todas las plantas. El estudio utiliza especies muy distantes evolutivamente, como son el alga Klebsormidium nitens, el briófito Marchantia polymorpha y la planta vascular Arabidopsis thaliana. El trabajo, del grupo del investigador Roberto Solano en el Centro Nacional de Biotecnología perteneciente al Consejo Superior de Investigaciones Científicas (CNB-CSIC), ha descubierto que la función original de las oxilipinas en cualquier planta es la activación de mecanismos de toleración de estrés térmico.
La supervivencia de las plantas en la naturaleza requiere su adaptación a diferentes tipos de estrés medioambiental. A diferencia de los animales, las plantas no tienen posibilidad de escapar cuando se enfrentan a una agresión externa como la mordedura de un insecto. Por este motivo, han desarrollado mecanismos de señalización interna y respuesta a través de hormonas como el ácido jasmónico. Sin embargo, la respuesta desencadenada por esta hormona frena el crecimiento de la planta para centrar los recursos en la defensa. Así, un exceso de acción de esta hormona puede afectar al desarrollo vegetal, por lo que su señalización debe estar regulada de una manera muy precisa en tiempo e intensidad.
Ahora, investigadores del Centro Nacional de Biotecnología (CNB) pertenecientes al Consejo Superior de Investigaciones Científicas (CSIC) en colaboración con las universidades de Estrasburgo y Navarra han identificado un nuevo mecanismo molecular que modula los pulsos de activación de la hormona. El trabajo, que ha sido publicado en la revista Proceedings of the National Academy of Sciences (PNAS), da respuesta a cómo se regula la activación de defensas hasta alcanzar un equilibrio entre crecimiento y respuesta a estrés.
CANCELADO
Debido al bajo número de solicitantes, se ha cancelado la realización del curso en el año 2020
El Centro Nacional de Biotecnología (CNB) del CSIC organiza un Curso de Formación del Profesorado, titulado “La biotecnología ante los retos de la sociedad actual”, destinado a profesores y catedráticos de enseñanza secundaria de la Comunidad de Madrid. En este curso multidisciplinar hablaremos del vertiginoso progreso del área de la biotecnología y de cómo está contribuyendo al bienestar de los ciudadanos. Contaremos con la participación de investigadores de prestigio internacional y reconocidos comunicadores científicos de nuestro instituto. El programa, ponentes y procedimiento de inscripción están aquí
Conscientes del interés que los avances científicos y tecnológicos suscitan en la sociedad, y del papel fundamental de los docentes en su transmisión a las nuevas generaciones, queremos con este contribuir a vuestra formación continua y a la difusión de conocimientos sobre un tema de tanta relevancia para la sociedad del siglo XXI.
Información adicional sobre el CNB, los ponentes y sus líneas de investigación, puede consultarse en la web del centro
Gracias al apoyo del programa de Excelencia Severo Ochoa, el Centro Nacional de Biotecnología (CNB-CSIC) ha sido capaz de fortalecer las infraestructuras de microscopía disponibles en el centro. La adquisición de nuevos equipos como microscopios ópticos avanzados y electrónicos de alta resolución van a permitir implementar nuevos enfoques utilizando técnicas de microscopía integradora y correlativa. De esta forma, se podrá abarcar un mayor rango de escalas y resoluciones múltiples, desde la anatomía macroscópica hasta el nivel unicelular, molecular y atómico. La estrecha colaboración entre los servicios de microscopia óptica avanzada, microscopía y criomocroscopía electrónica servirá de sinergia para el desarrollo de nuevas técnicas de microscopía correlativa en el CNB.
La nueva Unidad de Análisis de Datos de Bioimagen servirá para resolver los desafíos matemáticos necesarios para el procesamiento de datos procedentes de experimentos de imágenes de molécula única, microscopía óptica y electrónica. Además, el Centro de procesamiento de imágenes criogénicas de Instruct, la única instalación española perteneciente a INSTRUCT, la red europea de instalaciones de biología estructural, brinda apoyo continuo al procesamiento de datos de criomicroscopía.
Next Wednesday 29th of January, The CNB will host a simposium to honour Amelia Nieto, a CNB researcher from the origins of the center.
For her retirement, several researchers who initiated their scientific career in her group are visiting the CNB to celebrate the meeting "Looking at Cell Biology from a virus perspective".
This event count with speakers such as Maite Huarte, Tomás Aragón and Puri Fortes from the Centro de Investigaciones Médicas Aplicadas (CIMA) din Pamplona; Juan Varcarcel and Susana de la Luna from the Centre Reserca Genòmica (CRG) in Barcelona; aSantiago F. González from the Università della Svizzera in Bellinzona and Emilio Yángüez from the Functional Genomic Service at ETH in Zurich will join the .
This meeting is supported by The Company of Biologist through their Small Meeting Grant program.
Attendance is free
Carmen Elena Gómez, researcher at the Molecular and Cellular Biology Department received (ex aequo) the Research Prize from the Real Academia Nacional de Farmacia (RANF). The award ceremony took place in the Academia the 15th of January 2020.
This award recognises the research work “MVA-B as a model vaccine candidate against VIH/SIDA: From basic research to prophylactic and therapeutic clinical trials ”. Carmen Gómez explains "this review is focused in the Ankara modified version of vaccinia virus, collects our main contributions from the basic knowledge of the MVA vector biology, both in vitro and in vivo, to its evaluation as a vaccine candidate against HIV/AIDS in clinical trials. The work details the generation and characterization of the recombinant vector called MVA-B and the preclinical data that supported the evaluation of MVA-B as the first prophylactic and therapeutic vaccine against HIV-1 tested in humans in Spain. In addition, they assess the results of clinical trials and future lines of research on which to work considering the latest scientific advances in the field of vaccines against HIV.
In addition, professor Mariano Esteban has been distinguished with the Gold version of the Carracido Medal for his scientific and academic career, the highest award granted by the RANF. The award ceremony of the Carracido medal took place on Thursday, January 16th. In the act, he read his speech focused in "Vaccines as a disease control system: Where we are and where we are going". Afterwards, a painting by the Cantabrian Ricardo Sanjuán has been discovered to emphasize the work of Mariano Esteban as former President of the RANF (2013-2019)
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