Seminars Cycles
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Science & Society
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Mónica Chagoyen. Cuentos de telecomunicaciones (in Spanish) |
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Karel van Wely. Fumar perjudica seriamente a los cromosomas (in Spanish) |
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Miguel Vicente. Sin piedad: muere un enfermo de tuberculosis (in Spanish) |
Selected Publications
Science. The structure of native influenza ribonucleoproteins
EMBO Molecular Medicine. Publican las conclusiones para prevenir otro brote de E. coli como el de 2011 en Alemania
PNAS. p38γ y p38δ son claves en la respuesta inmunitaria
Developmental Cell. El citoesqueleto regula la expresión génica
The CNB in the Media
La Información. Lo importante de la clonación terapéutica es lo que viene (in Spanish)
RNE. A Hombros de Gigantes - Reportaje sobre el Centro Nacional de Biotecnología (in Spanish)
El País. La OMS advierte del contagio del nuevo coronavirus (in Spanish)
Biodiscover.com. Lluís Montoliu interviewed at the Transgenic Technology Meeting
The Guardian. Occam's Corner - Seeing inside the flu inside you
Meet our Scientists
Lluís Montoliu
ANIMAL MODELS BY GENETIC MANIPULATION
In our laboratory, we are interested in understanding how mammalian expression domains work and how they are organised within genomes. In particular, we focus on the identification and characterisation of genomic boundaries or insulators. By studying insulator elements, we aim to contribute to understanding of the functional and structural organization of vertebrate genomes. Insulators can be used effectively in biotechnological applications, as spacers, as boundaries, in any gene expression construct to be used in gene transfer experiments. They prevent inappropriate expression transgenes or gene therapy constructs and insulate them from neighbouring sequences at the insertion site in the host genomes. We are searching for new insulator sequences in vertebrate genomes, through initial bioinformatic analyses.
