Immunology & Oncology
DEPARTMENT
Research carried out in the Department of Immunology and Oncology (DIO) centres on characterizing the molecular and cellular bases of immune system function in inflammation and tumour development. Our general objective is to develop improved or new approaches for modulating the immune response during inflammatory reactions. We thus aim to identify new targets for prevention, diagnosis and treatment of inflammatory or autoimmune diseases and cancer.
Our common research objective provides an excellent environment and numerous opportunities for collaboration within the department as well as with other groups in the CNB (for example, the nanobiomedicine initiative). Since its origins, the DIO has maintained stable, productive collaborations with public and private partners that include prominent national and international research institutes, hospitals and pharmaceutical companies.
Head: Domingo F. Barber
Immunobiology of Monocytes, Macrophages and Dendritic Cells
Carlos Ardavín
Nanomedicine, Cancer Immunotherapy and Autoimmune diseases
Domingo F. Barber
Regulation of inflammation and autoimmunity by p21 and mitochondrial ROS
Dimitrios Balomenos
Yolanda Carrasco
Molecular Targets in Health and Disease, a Focus in PI3Kinase and NRF2
Ana Clara Carrera
Novel Modes of Intercellular Communication
Rubén García Martín
Antibody-based Agents for Cancer Immunotherapy
Leonor Kremer
Signaling Networks in Inflammation and Cancer
Santos Mañes
Mario Mellado
Innate Immunity to Viruses and Cancer
Hugh Reyburn
Mercedes Ricote
Tumour immune Activation and Evasion
Mar Valés-Gómez
Transcriptional Regulation of B Lymphocyte Differentiation
Ignacio Moreno de Alborán (temporarily abroad)