IP: Jorge Vicente
We are seeking a researcher interested in plant responses to stresses to address key questions about essential defence protein homeostasis during plant-pathogen interactions.
Project (N-MUNE – PID2022-139245OA-I00): Increasing pathogenic infections of crops has emerged as a grave threat to the international need of securing rising global food requirements. In this fight a fundamental goal is the identification of proteins that activate and enhance the plant immune response. However, little is known about how the stability of these proteins, that greatly affects their activity, is regulated.
This project, N-MUNE, will focus on the role of one biochemical system of protein degradation, the N-degron pathways, in pathogen sensing to control the plant immune response. The major goal of this project is to define how the stability of essential defence proteins is controlled by the N-degron pathways during the activation of the plant immune response against pathogens in Arabidopsis thaliana and tomato.
To achieve the objectives multidisciplinary approaches will be used, including molecular biology, transcriptomics, proteomics and analysis of pathogenic infections. The results will have future implications as they will provide a unique set of tools to help secure crop harvests.
Requirements: master’s degree or higher in Plant Biology or Biotechnology
Essential
– Knowledge of basic molecular biology techniques (Western Blot, PCR, qRT-PCR, cloning)
– Experience in plant molecular biology
– Ability to communicate and present scientific data
– To be an enthusiastic learner
Desirable
– Experience in plant-pathogen interactions
– Experience in CRISPR technology
– Experience in data analysis
Duration: 1.5 years (extendable depending on funding)
Applications until: 15th March
Start date : June 2025
Please send your CV, a cover letter and any question you might have about the position to jvicente@cnb.csic.es