Instruct Image Processing Centre

The Instruct Image Processing Centre (I2PC) is the reference laboratory for the image processing of Cryo-Electron Microscopy (CryoEM) acquired data within Instruct-ERIC (the European infrastructure for Structural Biology).

Our contribution is two-fold. On one-hand we develop infrastructure software for the support of image processing in CryoEM throughout Europe and the world. On the other hand, we serve the community by helping experimentalists to obtain three-dimensional structures of the biological macromolecules of their interest. These projects must be approved by Instruct and are channelled to us for their solution. Experimentalists can submit their data, come to learn how to process it, or even have a short internship (3-6 months) through Instruct. The I2PC is very active in giving training courses and seminars on all the image analysis techniques related to CryoEM. In the following we mention those access project that have required substantial extra involvement of Instruct staff and have led to actual joint publications, but the number of access projects not leading to publications is actually much larger (PID: 6258, PID:1395 in 2021 and PID: 16168, PID: 14989 in 2022).