La Fundación Lilly incorpora a Lluís Montoliu, investigador del CNB-CSIC, a su Consejo Científico, y destaca, entre otros aspectos, su gran experiencia colaborando con asociaciones de pacientes. Esta faceta aportará puntos de vista complementarios, tanto científicos como humanistas, a los temas que se debaten habitualmente en el consejo asesor de la Fundación. Con la incorporación de Montoliu son 14 las personalidades que forman parte del Consejo Científico presidido por Mariano Barbacid.
Entre los objetivos de la Fundación Lilly destaca el fomento de la ciencia, el impulso la medicina y la promoción de los valores del humanismo científico.
- Un estudio internacional liderado por científicos españoles descifra el origen de la herramienta de edición genética CRISPR y constata su actividad original
- El trabajo, publicado en la prestigiosa revista científica Nature Microbiology, abre nuevas vías en la manipulación de ADN y en el tratamiento de enfermedades como el cáncer o la diabetes
Un grupo de investigación internacional ha reconstruido por primera vez ancestros del conocido sistema CRISPR-Cas de hace 2.600 millones de años y ha estudiado su evolución a lo largo del tiempo. Los resultados apuntan a que los sistemas revitalizados no solo funcionan, sino que son más versátiles que las versiones actuales y podrían tener aplicaciones revolucionarias. La prestigiosa revista científica Nature Microbiology ha dado a conocer los resultados de esta investigación que, en opinión del equipo investigador “abre nuevas vías para la edición genética”.
En el proyecto, dirigido por el investigador Ikerbasque de CIC nanoGUNE Rául Pérez-Jiménez, participan equipos del Consejo Superior de Investigaciones Científicas como el de Lluís Montoliu en el Centro Nacional de Biotecnología, la Universidad de Alicante, el Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), el Hospital Ramón y Cajal-IRYCIS y otras instituciones estatales e internacionales.
Lluís Montoliu, investigador del CNB-CSIC, recibe hoy el Premio COSCE a la Difusión de la Ciencia 2022, otorgado por la Confederación de Sociedades Científicas Españolas (COSCE) con la colaboración de la Fundación Ramón Areces.
El biotecnólogo y genetista Lluís Montoliu, del Centro Nacional de Biotecnología (CNB-CSIC), es el nuevo presidente del Comité de Ética del Consejo Superior de Investigaciones Científicas (CSIC). El nuevo comité tendrá como vicepresidenta a la investigadora Carme Torras, matemática experta en inteligencia artificial y robótica del Instituto de Robótica e Informática Industrial (IRI-CSIC-UPC) de Barcelona. Montoliu y Torra toman el relevo del biólogo molecular Miguel García Guerrero, del Instituto de Bioquímica Vegetal y Fotosíntesis (IBVF-CSIC) y del microbiólogo Rafael Giraldo (CNB-CSIC). El CSIC da las gracias al equipo saliente por su labor a lo largo de los años, y da la bienvenida a la nueva presidencia.
This award from the European Society for Pigment Cell Research (ESPCR) and the International Federation of Pigment Cell Societies (IFPCS) aims to recognize the contribution of international researchers in the field of genetic conditions related to pigmentation.
Lluís Montoliu, CNB-CSIC and CIBERER researcher, received this year the medal for his “key efforts to use animal transgenics to investigate albinism. He has also been an untiring champion for people with albinism and is working on developing tools for improved diagnosis of albinism
Montoliu appreciated the recognition “it is a great honor to be awarded the HS Raper Medal remembering the memory of Henry Stanley Raper, a prestigious US biochemist best known for his pioneer work on the metabolism of fat and the formation of melanin.
Due to the cancellation of the International Pigmentation Congress that was to be held in Japan these days, the award ceremony had to be canceled, but the medal has already reached its recipient.
Lluís Montoliu, researcher at the CNB, has received one of the Antama Foundation Prizes in Science Dissemination. These prizes aim to recognise the role of journalists, scientists and initiatives that have contributed rigorously to the communication of science.
During the award ceremony, held the 5th of November in Madrid, Lluís Montoliu remarked that “we live an exciting time of continuous scientific and technological advances. Many of these biotechnology advances improve our quality of life, have a direct impact in how we can prevent and find cure for diseases, an optimal and sustainable use of the environment or improvements in animal and plant production necessary to meet the feeding needs of people and animals. ”
The Antama Foundation also recognised the work of Naukas, Maldita ciencia, Big Van Ciencia, Hipertextual, José Miguel Mulet, Álvaro Bayón, José Manuel López Nicolás, Rocío Vidal, Aitor Gálvez, Daniel García, Rosa Porcel, Sandra Ortonoves and Jorge Alcalde.
Francis Mojica, who discovered the potential of CRISPR tools, received an Honorary Award in "recognition of his decisive contribution to the advancement of genetic editing."
Dr. Lluis Montoliu has received this week in Japan the 12th ISTT Prize from The International Society for Transgenic Technologies (ISTT). The ISTT Prize is awarded to investigators who have made outstanding contributions to the field of transgenic technologies. The Award Committee recognised not only his seminal work on YAC transgenesis but also his efforts to develop and establish the ISTT, an organization now counting with more than 700 members worldwide where Dr. Montoliu served as the first President from 2006 to 2014.
Experts from across the continent recommend establishment of a European committee to review and evaluate the uses of new genetic tools. The new techniques are inexpensive, simple, rapid and have greatly expanded the range of potential applications; they are also moving millions of euros. Scientists consider it is time to launch a debate on the ethical and social implications of these tools, and to legislate their use and applicability.
3 million Spaniards suffer from one of the diseases classified as rare. Albinism is one of these and affects 1 in every 17,000 inhabitants. At the Centro Nacional de Biotecnología (CNB-CSIC), Lluis Montoliu’s laboratory seeks to broaden our knowledge of this disease to improve diagnosis and find customized therapies for these patients. The CNB-CSIC joins the celebration of this day to promote understanding and social awareness of these diseases.
Curr Protoc Hum Genet. 2014; 83:15.7.1-15.7.27.
Harms DW, Quadros RM, Seruggia D, Ohtsuka M, Takahashi G, Montoliu L, Gurumurthy CB.
The availability of techniques to create desired genetic mutations has enabled the laboratory mouse as an extensively used model organism in biomedical research including human genetics. A new addition to this existing technical repertoire is the CRISPR/Cas system. Specifically, this system allows editing of the mouse genome much more quickly than the previously used techniques, and, more importantly, multiple mutations can be created in a single experiment.
Here we provide protocols for preparation of CRISPR/Cas reagents and microinjection into one-cell mouse embryos to create knockout or knock-in mouse models.
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