PLoS ONE Nájera JL, Gómez CE, García-Arriaza J, Sorzano CO & Esteban M . The highly attenuated vaccinia virus strain NYVAC expressing HIV-1 components has been evaluated as a vaccine candidate in preclinical and clinical trials with encouraging...
Journal of Bacteriology Marín E, Bodelón G & Fernández LA . Autotransporters (ATs) are the largest group of proteins secreted by Gram-negative bacteria and include many virulence factors from human pathogens . ATs are synthesized as large precursors...
The FASEB Journal Arechaga I, Martínez-Costa OH, Ferreras C, Carrascosa JL & Aragón JJ. Phosphofructokinase is a sophisticated allosteric enzyme that is fundamental for the control of glycolysis . The structure of the bacterial enzyme is well...
Methods in Molecular Biology Sauer M & Friml J. Rapid advances in the field of plant biology, especially in plant cell biology, have created the need for methods that allow the localization of proteins in situ at subcellular resolution. Although in...
Journal of Interferon & Cytokine Research Domingo-Gil E, González JM & Esteban M . Interferon (IFN) type I induces the expression of antiviral proteins such as 2',5'-oligoadenylate synthetases (OAS). The enzyme OAS is activated by dsRNA to produce...
Antimicrobial Agents and Chemotherapy Rodríguez-Rojas A, Couce A & Blázquez J . Chronic infections caused by Pseudomonas aeruginosa are probably the most recurrent clinical situation where antibiotic treatment fails. The presence of hypermutable...
Biochim Biophys Acta Bannenberg G & Serhan CN. A new genus of specialized pro-resolving mediators (SPM) which include several families of distinct local mediators (lipoxins, resolvins, protectins, and maresins) are actively involved in the clearance...
Proteomics Medina-Aunon JA, Paradela A, Macht M, Thiele H, Corthals G & Albar JP . One of the main goals in proteomics is to solve biological and molecular questions regarding a set of identified proteins. In order to achieve this goal, one has to...
Journal of Virology Luque D, González JM, Garriga D, Ghabrial SA, Havens WM, Trus B, Verdaguer N, Carrascosa JL & Castón JR . Penicillium chrysogenum virus (PcV), a member of the Chrysoviridae family, is a double-stranded RNA (dsRNA) fungal virus with...
Biochimica et Biophysica Acta Pradet-Balade B, Leberbauer C, Schweifer N, Boulmé F. We took advantage of a mouse erythroid differentiation system to determine the relative contribution of transcriptional and translational control during this process....
Journal of Virology Guerra S, González JM, Climent N, Reyburn H, López-Fernández LA, Nájera JL, Gómez CE, García F, Gatell JM, Gallart T & Esteban M . The aim of this study was to define the effects on antigen-presenting cells of the expression of HIV...
Journal of Virology Resa-Infante P, Recuero-Checa MA, Zamarreño N, Llorca O & Ortín J . Replication and transcription of influenza A virus is carried out by ribonucleoproteins (RNPs) containing each genomic RNA segment associated to nucleoprotein...
Antimicrobial Agents and Chemotherapy Alvarez-Ortega C, Wiegand I, Olivares J, Hancock RE & Martínez JL . The resistome of P. aeruginosa for three beta-lactam antibiotics, namely ceftazidime, imipenem and meropenem was deciphered by screening a...
Journal of Molecular Biology Cuesta I, Núñez-Ramírez R, Scheres SH, Gai D, Chen XS, Fanning E & Carazo JM The Simian virus 40 (SV40) large tumor antigen (LTag) functions as the replicative helicase and initiator for viral DNA replication. For SV40...
Immunological Reviews Domínguez PM & Ardavín C Although monocytes were originally described as precursors to all the different subpopulations of macrophages found in the steady state and formed under inflammatory and infectious conditions, recent data...
Philos Trans R Soc Lond B Biol Sci Pagán I, Fraile A , Fernandez-Fueyo E, Montes N, Alonso-Blanco C & García-Arenal F. Understanding plant-virus coevolution requires wild systems in which there is no human manipulation of either host or virus. To...
Trends in Biochemical Sciences Sabio G & Davis RJ. The cJun NH 2 -terminal kinase isoform JNK1 is implicated in the mechanism of obesity-induced insulin resistance. Feeding a high-fat diet causes activation of the JNK1 signaling pathway, insulin...
The FASEB Journal Mañes S , Fuentes G, Peregil RM, Rojas AM & Lacalle RA. Type I phosphatidylinositol 4-phosphate 5-kinase (PIP5KI)- participates in establishing polarity during leukocyte chemotaxis. Its final 83 amino acids localize PIP5KI to the...
Plasmid Lioy VS, Rey O, Balsa D, Pellicer T & Alonso JC . The emergence and spread of pathogenic bacteria that have become resistant to multiple antibiotics through lateral gene transfer have created the need of novel antimicrobials. Toxin–antitoxin...
Journal of Experimental Botany Méndez-Vigo B, Andrés MT, Ramiro M, Martínez-Zapater JM & Alonso-Blanco C . Vegetative growth and flowering initiation are two crucial developmental processes in the life cycle of annual plants that are closely...
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