Microb Biotechnol. 2023 Nov 16. L Cerdán, B Álvarez, LA Fernández Abstract Large gene libraries are frequently created in Escherichia coli plasmids, which can induce cell toxicity and expression instability due to the high gene dosage. To address these...
Anal Chem. 2023 Nov 14;95(45):16692-16700. C Escalona-Noguero, H Alarcón-Iniesta, M López-Valls, LP Del Carpio, JM Piulats, Á Somoza, B Sot Abstract Uveal melanoma (UM) is a rare ocular tumor characterized by high metastasis risk and poor prognosis....
ACS Nano. 2023 Nov 8. V Castro, AJ Pérez-Berna, G Calvo, E Pereiro, P Gastaminza Abstract Plus-strand RNA viruses are proficient at remodeling host cell membranes for optimal viral genome replication and the production of infectious progeny. These...
Int J Antimicrob Agents. 2023 Nov 3:107027. T Gil-Gil, JL Martínez Abstract The inducible transporters UhpT and GlpT are accepted as the unique fosfomycin inner membrane cellular transporters. Accordingly, it has been traditionally accepted that...
Pharmaceutics. 2023 Oct 13;15(10):2459. A Gómez-Moreno, E San Sebastian, J Moya, P Gomollón-Zueco, S Isola, Á Vales, G González-Aseguinolaza, C Unzu , U Garaigorta Abstract Gene therapy is a promising strategy to treat and cure most inherited metabolic...
Invest Ophthalmol Vis Sci . 2023 Oct 3;64(13):32. A Guardia, A Fernández, D Seruggia, V Chotard, C Sánchez-Castillo, O Kutsyr, X Sánchez-Sáez, E Zurita, M Cantero, A Rebsam, N Cuenca, L Montoliu Abstract Purpose: We aimed to generate and phenotype a...
Nucleic Acids Res. 2023 Sep 18:gkad758. B Blázquez, D San León, J Torres-Bacete, Á Gómez-Luengo, R Kniewel, I Martínez, S Sordon, A Wilczak, S Salgado, E Huszcza, J Popłoński, A Prieto, J Nogales Abstract Modular cloning has become a benchmark...
Commun Biol. 2023 Sep 9;6(1):923. S Castanheira, F García-Del Portillo Abstract Cell shape is genetically inherited by all forms of life. Some unicellular microbes increase niche adaptation altering shape whereas most show invariant morphology. A...
Nat Commun. 2023 Sep 5;14(1):5436. L Velasco-Carneros, J Cuéllar, L Dublang, C Santiago, J-D Maréchal, J Martín-Benito, M Maestro, JÁ Fernández-Higuero, N Orozco, F Moro, JM Valpuesta, A Muga Abstract J-domain proteins tune the specificity of Hsp70s,...
mBio 2023 Aug 25:e0045123. M Bello-Perez , J Hurtado-Tamayo , AZ Mykytyn , MM Lamers , R Requena-Platek , D Schipper , D Muñoz-Santos , J Ripoll-Gómez , A Esteban , J Sánchez-Cordón , L Enjuanes , BL Haagmans , I Sola Abstract Severe acute respiratory...
Chaos, Solitons & Fractals 174, September 2023, 113800 Iker Atienza, Luis F Seoane Abstract The vertebrate immune system is capable of strong, focused adaptive responses that depend on T-cell specificity in recognizing antigenic sequences of a...
Science. 2023 Jul 21;381(6655):343-348. Chang-Yu Chang, Djordje Bajić, Jean C C Vila, Sylvie Estrela, Alvaro Sanchez Abstract Understanding the mechanisms that maintain microbial biodiversity is a critical aspiration in ecology. Past work on microbial...
ACS Appl Mater Interfaces. 2023 Jul 12;15(27):32162-32176. David Egea-Benavente, Carlos Díaz-Ufano, Álvaro Gallo-Cordova, Francisco Javier Palomares, Jhon Lehman Cuya Huaman, Domingo F Barber, María Del Puerto Morales, Jeyadevan Balachandran Abstract...
ACS Appl Mater Interfaces. 2023 Aug 2;15(30):35906-35926. Yadileiny Portilla, Vladimir Mulens-Arias, Neus Daviu, Alberto Paradela, Sonia Pérez-Yagüe, Domingo F Barber Abstract Upon contact with biological fluids like serum, a protein corona (PC)...
Elife. 2023 Jul 17;12:e86200. Alejandra Escós, Ester Diaz-Mora, Michael Pattison, Pilar Fajardo, Diego González-Romero, Ana Risco, José Martín-Gómez, Éric Bonneil, Nahum Sonenberg, Seyed Mehdi Jafarnejad, Juan José Sanz-Ezquerro, Steven C Ley, Ana...
Antimicrob Agents Chemother . 2023 Jul 18;67(7):e0039423. Brenda Martínez-González , Isabel Gallego, Josep Gregori, María Eugenia Soria, Pilar Somovilla, Ana Isabel de Ávila, Carlos García-Crespo, Antoni Durán-Pastor, Carlos Briones, Jordi Gómez, Josep...
ACS Synth Biol. 2023 Jun 16;12(6):1579-1582 . AD Hanson, V de Lorenzo Abstract Synthetic biology (SynBio) has attracted like no other recent development the attention not only of Life Science researchers and engineers but also of intellectuals,...
Nucleic Acids Res. 2023 May 13;gkad405. J Lopez-Ibañez, F Pazos, M Chagoyen Abstract MBROLE (Metabolites Biological Role) facilitates the biological interpretation of metabolomics experiments. It performs enrichment analysis of a set of chemical...
ACS Synth Biol. 2023 Jun 16;12(6):1667-1676. Epub 2023 May 17. A Hueso-Gil, BCalles, V de Lorenzo Abstract The inner physicochemical heterogeneity of bacterial cells generates three-dimensional (3D)-dependent variations of resources for effective...
Nat Commun. 2023 Mar 30;14(1):1723. Sara Hernando-Amado, Pablo Laborda, José Luis Martínez Abstract Collateral sensitivity (CS) is an evolutionary trade-off traditionally linked to the mutational acquisition of antibiotic resistance (AR). However, AR...
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