The macromolecular X-ray crystallography facility provides the following techniques:
Advice and supervision on protein production from cloning to expression in bacterial, yeast and eukaryotic systems
Support and training on protein purification to obtain crystal-grade protein for crystallization
Automated macromolecular crystallization
Crystallization conditions optimization applying standard and in-house techniques
Crystal mounting. Access to synchrotron beam time. X-ray diffraction data collection
Data processing and structure resolution and analysis
Service equipment: • Three temperature controlled crystallization rooms • Genesis RSP 150 workstation (Tecan Trading AG) nanodispenser robot • Rigaku Desktop Minstrel™ system for automated crystallization plates visualization • CrystalTrakTM database suite for crystallization screening and improvement of positive trials
