Pablo Gastaminza

INFECCIÓN POR EL VIRUS DE LA HEPATITIS C

Our laboratory is interested in deciphering the molecular events underlying the functional dependence of HCV infection on lipid and lipoprotein metabolism and how to exploit these pathways to inhibit HCV infection. We use a cell culture infection system based on the infectious molecular clone JFH-1 and the Huh-7 hepatoma cell line and derived subclones to evaluate the impact that genetic and pharmacological manipulation of cellular lipid metabolism has on HCV infection and pathogenesis.