Ana Clara Carrera

MOLECULAR TARGETS IN HEALTH AND DISEASE, A FOCUS IN PI3-QUINASE

Two biological problems have occupied the activity of our team (~12 to 15 members): cancer and inflammation. Our recent work is based in the assumption that the same biological activities that control physiological responses also control pathology when deregulated. The team is currently working on class I phosphoinositide 3-kinase (PI3K), with special emphasis on examining the specific function of each of the four class I PI3K isoforms in physiology and disease.