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SANITAS:
Screening Assays for New Bacterial Inhibitors Based on Targets Active in Septation
European Commission, QLK3-CT-2000-00079

SANITAS_leaflet Download SANITAS leaflet
 

The acronym, SANITAS means health. It is formed from the project title "Screening Assays for New Bacterial Inhibitors Based on Targets Active in Septation"

The goal of the SANITAS project is to screen for compounds able to inhibit bacterial proliferation by blocking cell division. We use as targets several molecules that are essential for the formation of the division septum.

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Summary:

 
Screens that use existing and novel assays based on recent knowledge on bacterial division will be developed and used to search for antibacterials.

New knowledge derives from the application of novel technologies (genomics, bioinformatics, structural biology, screening technologies).

Natural product, synthetic compound, and "biased" chemical libraries will be screened to select candidate molecules for development as antibiotics.

Results on the biochemical activities of targeted division proteins, and on their structures will provide structure-activity relationship data for the chemical optimisation of lead compounds. 

The participation of a  leading pharmaceutical company guarantees the link between the generation of results and the ability to exploit them for the benefit of the end consumer.

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Partnership:
 
 
 

Participant number Institution Group leader
1a, and coordinator 
 Centro Nacional de Biotecnología .
CSIC. Madrid. Spain		 Miguel Vicente

1b
 Centro Nacional de Biotecnología .
CSIC. Madrid. Spain		 Alfonso Valencia

2
 Aventis. Romainville.
France		 John Hodgson

3
 MRC Laboratory of Molecular Biology. Cambridge.
United Kingdom		 Jan Löwe

4a
 Max Planck Institute.
Tübingen. Germany		 Joachim V. Höltje

4b

 Universität Tübingen. Germany
 Friedrich Götz




5
 Universitá de Cagliary.
Italy		 Orietta Massidda

6
 University of Brussels. Belgium Jean-Marie Ruysschaert

 
 
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Technical data:

Maximun Community contribution: 1,453,932 EURO
Estimated eligible costs: 2,445,454 EURO
Starting date: 1 March 2001
Finishing date: 29 February 2004
Number of persons/month (research): 435
Number of persons/month (coordination): 30
 

 
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News:
 
 
 

Meetings calendar*

Year 2001
8 June: 
First Group Leaders Meeting, Hotel Majadahonda. Majadahonda, Spain

Year 2002
28 February - 1 March
First Team Meeting, Hotel Semiramis. Puerto de la Cruz. Tenerife, Spain
28 June: 
2nd Group Leaders Meeting, VIRTUAL MEETING
17 - 18 October 
Second Team Meeting, Hotel Baia di Nora.  Sardinia, Italy

Year 2003
23 May 
3rd Group Leaders Meeting, Aventis Pharma, Romainville, France 
25 - 26 September
Final Workshop.  Sheraton Hotel and Towers. Brussels

* all the meetings were CLOSED

 

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Secretary:

Aurora Cabrerizo
Centro Nacional de Biotecnología
tel. +34 91 585 46 98
fax +34 91 585 45 06
e-mail:  acabreri@cnb.uam.es
 

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Photo from Puerto de la Cruz

            Teide
 

Photos from Baia di Nora:

hotel
  participants
     Nora
    spanish tower
    roman street
       Su Nuraxi complex
     Su Nuraxi village
 

Photo from Brussels:

Brussels Grand Place      Grand Place

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FAQs: all what as a scientist you never wanted to know about European Projects, but the administrators force you to ask.

This section provides  a link to a QuickTime movie created from a presentation by the CSIC Office for European Commission Projects.

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Links to "Genetic Control of the Cell Cycle" pages:

Home, Welcome, Building bocks, Timing, Curing diseases, Group members, Technical data, Links


created by STUDIO MV
last update: 27 July 2004