Departamento de Biología Molecular y Celular
Department of Molecular and Cellular Biology
CNB-CSIC

Lab. Dr. Amelia Nieto

Tel. +34 915854914 (office) / Tel. +34 915854533 (lab.)
Fax. +34 915854506

Laboratory WEB page



Objetivos / Aims

La interacción del virus de la gripe con las células infectadas.
The interaction of influenza virus with infected cells.

Memoria Científica 2003-2004

Research Summary 2003-2004


Personal / Staff

Amelia Nieto Martín
Ariel Rodríguez
Thomas Lutz
Idoia Burgui Herrera
Alicia Pérez González
Emilio Yángüez


Publicaciones recientes / Recent Publications:

Burgui I, Aragon T, Ortin J, Nieto A.(2003)
PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes.
Journal of General Virology 84:3263-3274.

Huarte M, Falcon A, Nakaya Y, Ortin J, Garcia-Sastre A, Nieto A.(2003)
Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses.
Journal of Virology 77(10):6007-6013.

Huarte M, Sanz-Ezquerro JJ, Roncal F, Ortin J, Nieto A. (2001)
PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators.
Journal of Virology 75(18):8597-604.

Aragon T, de la Luna S, Novoa I, Carrasco L, Ortin J, Nieto A. (2000)
Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus.
Molecular and Cellular Biology 20(17):6259-6268.

Perales B, Sanz-Ezquerro JJ, Gastaminza P, Ortega J, Santaren JF, Ortin J, Nieto A. (2000)
The replication activity of influenza virus polymerase is linked to the capacity of the PA subunit to induce proteolysis.
Journal of Virology 74(3):1307-1312.



Last update: 14 February 2006
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